hrp0084p3-687 | Diabetes | ESPE2015

Correlation of Vitamin D Levels with Glycaemic Control, Total Daily Insulin Dose, BMI, and Ethnicity in Paediatric Patients with Type 1 Diabetes Mellitus

Bianco Monica , Durazo Ramon , Durazo-Arvizu Ramon , Minutti Carla

Background: Type 1 diabetes mellitus (T1DM) is an autoimmune and inflammatory process and vitamin D (VD) is thought to reduce inflammation and prevent autoimmune destruction. Studies have shown that VD has an effect on insulin secretion and sensitivity in rats. And it has been shown that adult T2DM with normal levels of VD have decreased insulin requirements. Two prior studies in Turkey looked at the relationship between VD levels and daily insulin requirement in paediatric pa...

hrp0084p3-759 | Diabetes | ESPE2015

Short-Term Use of Continuous Glucose Monitoring System in Paediatric Patients with Type 1 Diabetes Mellitus and Correlation with Short-Term Improvement in Glycaemic Control

Bianco Monica , Alesia Teresa , Durazo-Arvizu Ramon , Minutti Carla

Background: Several studies show there may be a relationship between the use of continuous glucose monitoring systems (CGMS) and improved glycaemic control in patients with type 1 diabetes mellitus (t1dm).Objective and hypotheses: The purpose of this study was to determine if there is a significant correlation between the clinical (office based) use of short-term CGMS and improvement in glycaemic control in paediatric patients with t1dm.<p class="abs...

hrp0095lb5 | Late Breaking | ESPE2022

Incidence and Severity of Type 1 Diabetes Mellitus during COVID-19 Pandemic

Dieguez Abigayil , DeLacey Sean , Lado Juan , Levin Laura , Ranganna Adesh , Wu Margaret , E. Bianco Monica

Background: The COVID-19 pandemic continues to impact healthcare overall particularly in relation to diabetes. Initial studies showed delays in emergent healthcare utilization, decreased preventative care visits, and more severe presentations of new onset diabetes. However, the pathophysiologic relationship between COVID-19 and type 1 diabetes is not yet well understood.Objectives: Our primary objective was to compare th...

hrp0095lb22 | Late Breaking | ESPE2022

Maternal and Cord Blood Metabolites Associations with Childhood Glucose Outcomes in the Hyperglycemia and Adverse Pregnancy Outcome Follow-up Study.

E. Bianco Monica , Hai My , Scholtens Denise , Josefson Jami , Lowe William , Jr

Background: Maternal triglycerides, fatty acids, and their metabolites together with sugars and metabolic intermediates may play a role in newborn outcomes. Furthermore, maternal amino acids, acylcarnitines, lipids and fatty acids and their metabolites are associated with cord C-peptide independent of maternal BMI and glycemia, highlighting the potential contribution of maternal metabolites to offspring outcomes. This study examined the associations of materna...